Overview

SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.3
USERS' SCORE
Moderately Good
Based on 84 Reviews
7.8
Supplement Facts
Serving Size:  3 Tablets
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
100 mg
111%
Calcium (from Calcium Phosphate, Calcium Stearate)
30 mg
2%
L-Lysine (from L-Lysine Hydrochloride)
1.5 g
Garlic Bulb (deodorized)
200 mg
Echinacea purpurea Aerial Parts Extract 4:1 
100 mg
Propolis 
25 mg
Licorice Root Extract 4:1
15 mg

Top Medical Research Studies

8
Lysine helps reduce cold sore outbreaks
We examined the effectiveness of long-term lysine supplementation for preventing cold sores, specifically in individuals with a history of frequent outbreaks. Over a 12-month period, twenty-six volunteers participated in a double-blind study, taking daily doses of 1,000 mg of lysine.

Our findings indicated that those taking lysine experienced significantly fewer lesions compared to the control group. Moreover, when participants stopped the supplementation, their outbreaks increased. Maintaining serum lysine levels above 165 nmol/ml appeared crucial for effectiveness, highlighting lysine's potential benefits in managing recurrent cold sores.
Read More
9
Lysine shows potential for herpes relief
We surveyed 1,543 individuals over six months to explore the impact of lysine on herpes infections, including cold sores. Participants averaged a daily dose of 936 mg of lysine. An impressive 84% reported that this supplement either prevented recurrence or reduced the frequency of outbreaks. When comparing symptoms, 79% found them severe without lysine, while only 8% felt the same when using it. Healing times improved dramatically—90% took six to 15 days to heal without lysine, but 83% healed in five days or less with it. Overall, 88% deemed lysine an effective treatment.
Read More
4
L-lysine lacks preventive effectiveness
We explored whether L-lysine can effectively prevent cold sores caused by the herpes simplex virus. Two researchers conducted a thorough literature review, examining various clinical studies.

Despite the interest, our findings indicate that L-lysine supplements, particularly less than 1 g per day, are ineffective for preventing outbreaks. Interestingly, higher doses, exceeding 3 g per day, were reported to enhance patients' overall experience with the condition.

However, we believe more extended studies focusing on higher dosages are necessary for conclusive results, especially for those with specific health concerns.
Read More

Most Useful Reviews

9
Excellent immune formula
18 people found this helpful
Repeat purchase. An excellent immune formula that I have bought twice already. It helped me at the first sign of a cold. As soon as my throat started to hurt, I took three capsules before bed and felt better by morning. It contains lysine, vitamin C, calcium, propolis, and echinacea extract.
Read More
9
Immune system support
18 people found this helpful
Magic tablets! After moving to a different climate, my immune system weakened, and I fell ill every month. I tried various remedies but found no relief until I discovered these vitamins. Reducing the dose allowed me to stretch them over three months, and since January 2015, I haven’t been sick at all!
Read More
9
Miracle for cold sores
14 people found this helpful
I’ve suffered from cold sores for years and usually relied on valacyclovir. Desperate, I tried Lysine after reading positive reviews. After taking six pills for a few days, the tingling and pain disappeared, and the blisters were completely gone after five days. This will be a staple in my medicine cabinet.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.3
  • All Researches
9
L-lysine shows promise for cold sores
We examined the effects of L-lysine, paired with botanicals and nutrients, on cold sores caused by the herpes virus. In this pilot study, 30 participants tracked symptoms like itching and soreness, revealing impressive results. By the third day, 40% experienced complete healing, which rose to 87% by day six. While most showed significant improvement, a couple did not respond as well. Importantly, the study had no reported adverse effects, showing that L-lysine could effectively ease cold sore symptoms.
Read More
9
Lysine shows potential for herpes relief
We surveyed 1,543 individuals over six months to explore the impact of lysine on herpes infections, including cold sores. Participants averaged a daily dose of 936 mg of lysine. An impressive 84% reported that this supplement either prevented recurrence or reduced the frequency of outbreaks. When comparing symptoms, 79% found them severe without lysine, while only 8% felt the same when using it. Healing times improved dramatically—90% took six to 15 days to heal without lysine, but 83% healed in five days or less with it. Overall, 88% deemed lysine an effective treatment.
Read More
8
Lysine helps reduce cold sore outbreaks
We examined the effectiveness of long-term lysine supplementation for preventing cold sores, specifically in individuals with a history of frequent outbreaks. Over a 12-month period, twenty-six volunteers participated in a double-blind study, taking daily doses of 1,000 mg of lysine.

Our findings indicated that those taking lysine experienced significantly fewer lesions compared to the control group. Moreover, when participants stopped the supplementation, their outbreaks increased. Maintaining serum lysine levels above 165 nmol/ml appeared crucial for effectiveness, highlighting lysine's potential benefits in managing recurrent cold sores.
Read More
4
L-lysine helpful for prevention
We investigated how dietary changes and supplements affect skin conditions, focusing on cold sores. The review highlighted L-lysine’s benefits as a preventive measure, which may help ward off outbreaks. However, we found that it doesn't shorten the healing time of existing lesions. While there's plenty of anecdotal support, rigorous evidence remains limited for many dietary interventions in treating skin issues. Understanding these nutritional influences can guide us toward effective management options for cold sores.
Read More
4
L-lysine lacks preventive effectiveness
We explored whether L-lysine can effectively prevent cold sores caused by the herpes simplex virus. Two researchers conducted a thorough literature review, examining various clinical studies.

Despite the interest, our findings indicate that L-lysine supplements, particularly less than 1 g per day, are ineffective for preventing outbreaks. Interestingly, higher doses, exceeding 3 g per day, were reported to enhance patients' overall experience with the condition.

However, we believe more extended studies focusing on higher dosages are necessary for conclusive results, especially for those with specific health concerns.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 84 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Excellent immune formula
18 people found this helpful
Repeat purchase. An excellent immune formula that I have bought twice already. It helped me at the first sign of a cold. As soon as my throat started to hurt, I took three capsules before bed and felt better by morning. It contains lysine, vitamin C, calcium, propolis, and echinacea extract.
Read More
9
Immune system support
18 people found this helpful
Magic tablets! After moving to a different climate, my immune system weakened, and I fell ill every month. I tried various remedies but found no relief until I discovered these vitamins. Reducing the dose allowed me to stretch them over three months, and since January 2015, I haven’t been sick at all!
Read More
9
Miracle for cold sores
14 people found this helpful
I’ve suffered from cold sores for years and usually relied on valacyclovir. Desperate, I tried Lysine after reading positive reviews. After taking six pills for a few days, the tingling and pain disappeared, and the blisters were completely gone after five days. This will be a staple in my medicine cabinet.
Read More
9
Miracle cure
7 people found this helpful
This drug is excellent! I’ve taken three tablets daily for two months and have forgotten what cold sores are like. My relapses, which used to occur twice a month, ceased, and I’ve managed to cure a cold before it developed. I wholeheartedly recommend it.
Read More
9
Cold-free for a year
5 people found this helpful
Loved this product! I took three tablets daily for a month and didn’t catch a cold for an entire year. I highly recommend it during the autumn virus season. The smell of garlic is subtle.
Read More

Frequently Asked Questions

9
Miracle for cold sores
14 people found this helpful
I’ve suffered from cold sores for years and usually relied on valacyclovir. Desperate, I tried Lysine after reading positive reviews. After taking six pills for a few days, the tingling and pain disappeared, and the blisters were completely gone after five days. This will be a staple in my medicine cabinet.
10
Rapid relief
3 people found this helpful
At the first signs of a cold or cold sores, we take extra doses and it typically resolves within three days, greatly reducing discomfort.
9
Reduced outbreaks
4 people found this helpful
I've struggled with cold sores since childhood and have tried countless remedies. However, after using this formula for a year, I see significant improvement. My outbreaks are half as frequent and much smaller. My partner caught colds, but I’ve stayed healthy. I can’t live without it now.
9
Quick results
2 people found this helpful
I take six tablets daily at the onset of a cold sore, and it never develops. This has been wonderful!
9
Cold-free for a year
5 people found this helpful
Loved this product! I took three tablets daily for a month and didn’t catch a cold for an entire year. I highly recommend it during the autumn virus season. The smell of garlic is subtle.
9
Essential for immunity
1 people found this helpful
Best supplement ever! I can't live without it! Since starting it, after experiencing Covid, my immune system has been strong, and I haven’t had any illness.
9
Effective treatment
2 people found this helpful
Very effective at treating cold sores. I take two tablets per hour when I sense the initial tingling of a cold sore and continue until healing begins. I also use topical calendula cream. I avoid arginine-rich foods (like nuts) to reduce cold sore frequency, as lysine and arginine can counteract each other in skin healing.
9
Reduces cold sores
2 people found this helpful
Since taking this for three years, I hardly get cold sores anymore and feel it helps me avoid illness overall. I also reduced l-arginine-rich foods to help suppress HSV. This is a vital supplement for me.
9
Magic for colds
1 people found this helpful
This stuff is magic! When I sense a sore throat or cold developing, I take it twice a day alongside another supplement and feel back to normal. It’s essential for cold and flu season!
8
Lysine helps reduce cold sore outbreaks
We examined the effectiveness of long-term lysine supplementation for preventing cold sores, specifically in individuals with a history of frequent outbreaks. Over a 12-month period, twenty-six volunteers participated in a double-blind study, taking daily doses of 1,000 mg of lysine.

Our findings indicated that those taking lysine experienced significantly fewer lesions compared to the control group. Moreover, when participants stopped the supplementation, their outbreaks increased. Maintaining serum lysine levels above 165 nmol/ml appeared crucial for effectiveness, highlighting lysine's potential benefits in managing recurrent cold sores.
9
Lysine shows potential for herpes relief
We surveyed 1,543 individuals over six months to explore the impact of lysine on herpes infections, including cold sores. Participants averaged a daily dose of 936 mg of lysine. An impressive 84% reported that this supplement either prevented recurrence or reduced the frequency of outbreaks. When comparing symptoms, 79% found them severe without lysine, while only 8% felt the same when using it. Healing times improved dramatically—90% took six to 15 days to heal without lysine, but 83% healed in five days or less with it. Overall, 88% deemed lysine an effective treatment.
4
L-lysine lacks preventive effectiveness
We explored whether L-lysine can effectively prevent cold sores caused by the herpes simplex virus. Two researchers conducted a thorough literature review, examining various clinical studies.

Despite the interest, our findings indicate that L-lysine supplements, particularly less than 1 g per day, are ineffective for preventing outbreaks. Interestingly, higher doses, exceeding 3 g per day, were reported to enhance patients' overall experience with the condition.

However, we believe more extended studies focusing on higher dosages are necessary for conclusive results, especially for those with specific health concerns.
4
L-lysine helpful for prevention
We investigated how dietary changes and supplements affect skin conditions, focusing on cold sores. The review highlighted L-lysine’s benefits as a preventive measure, which may help ward off outbreaks. However, we found that it doesn't shorten the healing time of existing lesions. While there's plenty of anecdotal support, rigorous evidence remains limited for many dietary interventions in treating skin issues. Understanding these nutritional influences can guide us toward effective management options for cold sores.

References

  1. Jamgochian M, Alamgir M, Rao B. Diet in Dermatology: Review of Diet's Influence on the Conditions of Rosacea, Hidradenitis Suppurativa, Herpes Labialis, and Vitiligo. Am J Lifestyle Med. 2023;17:152. doi:10.1177/15598276211026592
  2. Mailoo VJ, Rampes S. Lysine for Herpes Simplex Prophylaxis: A Review of the Evidence. Integr Med (Encinitas). 2017;16:42.
  3. Singh BB, Udani J, Vinjamury SP, Der-Martirosian C, Gandhi S, et al. Safety and effectiveness of an L-lysine, zinc, and herbal-based product on the treatment of facial and circumoral herpes. Altern Med Rev. 2005;10:123.
  4. Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol. 1984;58:659.
  5. Walsh DE, Griffith RS, Behforooz A. Subjective response to lysine in the therapy of herpes simplex. J Antimicrob Chemother. 1983;12:489.
  6. Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol. 1980;60:85.
image